When you try to access the FIM 2010 R2 portal you receive the following screen stating that "Service not available. Please contact your help desk or system administrator."
In the Event Logs there is a continuous error "Event 3, Microsoft.ResourceManagement" in the error states that "System.Net.WebException: Unable to connect to remote server ---->" and "No connection could be made because the target machine actively refused it 10.25.1.40:433." That IP was actually one of my Domain Controllers, so I disabled the Windows Firewall to see if it would resolve the error. No change unfortunately.
After a bit research with some travling through TechNet blogs I came across this link which is "A hotfix rollup package (build 4.1.3508.0) is available for Forefront Identity Management 2010 R2" http://support.microsoft.com/kb/2913228/en-us although my issue was not directly mentioned in th More Information section I though it would be best to install the updates for the components I had deployed.
I installed FIMSyncService_x64_KB2913228.exe first.
Then FIMService_x64_KB2913228 secondly.
After the second patch was applied the FIM portal then started to work.